Schedule
  | thursday 02.09.2021 Lokomotiv vs Dinamo R | 3:2(1:2, 1:0, 1:0) | Review |
 | saturday 04.09.2021 Lokomotiv vs SKA | 3:4 SO(1:1, 1:2, 1:0, 0:0, 0:1) | Review |
 | tuesday 07.09.2021 Lokomotiv vs Dinamo Mn | 3:4(0:2, 2:0, 1:2) | Review |
 | friday 10.09.2021 CSKA vs Lokomotiv | 3:1(2:0, 1:1, 0:0) | Review |
| sunday 12.09.2021 Dinamo R vs Lokomotiv | 0:4(0:4, 0:0, 0:0) | Review |
 | tuesday 14.09.2021 Jokerit vs Lokomotiv | 2:0(1:0, 0:0, 1:0) | Review |
 | saturday 18.09.2021 Lokomotiv vs Torpedo | 4:3(1:0, 0:1, 3:2) | Review |
| monday 20.09.2021 Lokomotiv vs Jokerit | 1:4(0:2, 1:1, 0:1) | Review |
 | wednesday 22.09.2021 Lokomotiv vs Vityaz | 2:3(0:1, 1:2, 1:0) | Review |
 | saturday 25.09.2021 Lokomotiv vs Salavat Yulaev | 2:3 OT(1:0, 1:1, 0:1, 0:1) | Review |
 | monday 27.09.2021 Avangard vs Lokomotiv | 1:4(1:0, 0:1, 0:3) | Review |
| wednesday 29.09.2021 Vityaz vs Lokomotiv | 1:4(0:0, 0:2, 1:2) | Review |
 | sunday 03.10.2021 Lokomotiv vs Barys | 4:3(2:2, 1:1, 1:0) | Review |
| tuesday 05.10.2021 SKA vs Lokomotiv | 1:0(0:0, 1:0, 0:0) | Review |
 | thursday 07.10.2021 Severstal vs Lokomotiv | 1:5(1:2, 0:2, 0:1) | Review |
 | monday 11.10.2021 Lokomotiv vs Dynamo Msk | 3:1(1:0, 1:0, 1:1) | Review |
| wednesday 13.10.2021 Lokomotiv vs Severstal | 2:1 OT(0:0, 1:1, 0:0, 1:0) | Review |
 | sunday 17.10.2021 Lokomotiv vs Kunlun Red Star | 4:3(3:0, 0:1, 1:2) | Review |
 | tuesday 19.10.2021 Lokomotiv vs Admiral | 1:3(0:1, 1:1, 0:1) | Review |
| friday 22.10.2021 Barys vs Lokomotiv | 1:4(0:1, 0:1, 1:2) | Review |
| sunday 24.10.2021 Salavat Yulaev vs Lokomotiv | 4:3 SO(0:1, 0:1, 3:1, 0:0, 1:0) | Review |
| tuesday 26.10.2021 Dynamo Msk vs Lokomotiv | 4:1(0:0, 3:0, 1:1) | Review |
 | thursday 28.10.2021 Lokomotiv vs Neftekhimik | 1:2 OT(1:0, 0:0, 0:1, 0:1) | Review |
 | sunday 31.10.2021 Lokomotiv vs Spartak | 4:2(0:0, 2:1, 2:1) | Review |
| tuesday 02.11.2021 Torpedo vs Lokomotiv | 3:2(1:1, 2:1, 0:0) | Review |
 | thursday 04.11.2021 Lokomotiv vs Metallurg Mg | 3:2(1:0, 2:1, 0:1) | Review |
 | sunday 07.11.2021 Lokomotiv vs Amur | 3:4 SO(1:0, 2:1, 0:2, 0:0, 0:1) | Review |
| monday 15.11.2021 Dinamo Mn vs Lokomotiv | 3:7(2:2, 1:3, 0:2) | Review |
| wednesday 17.11.2021 SKA vs Lokomotiv | 1:3(0:1, 0:1, 1:1) | Review |
 | friday 19.11.2021 HC Sochi vs Lokomotiv | 1:3(0:1, 1:1, 0:1) | Review |
| sunday 21.11.2021 Neftekhimik vs Lokomotiv | 1:0(1:0, 0:0, 0:0) | Review |
| wednesday 24.11.2021 Lokomotiv vs Jokerit | 2:1(0:0, 1:1, 0:0, 1:0) | Review |
 | friday 26.11.2021 Lokomotiv vs Traktor | 1:2 OT(1:0, 0:0, 0:1, 0:1) | Review |
| sunday 28.11.2021 Jokerit vs Lokomotiv | 2:0(0:0, 0:0, 2:0) | Review |
| tuesday 30.11.2021 Spartak vs Lokomotiv | 19:30 | |
| thursday 02.12.2021 CSKA vs Lokomotiv | 19:30 | |
 | monday 06.12.2021 Lokomotiv vs Sibir | 19:30 | Tickets |
| wednesday 08.12.2021 Lokomotiv vs Avangard | 19:30 | Tickets |
 | friday 10.12.2021 Lokomotiv vs Avtomobilist | 19:00 | Tickets |
| sunday 12.12.2021 Lokomotiv vs CSKA | 17:00 | Tickets |
| tuesday 21.12.2021 Sibir vs Lokomotiv | 15:30 | |
| thursday 23.12.2021 Admiral vs Lokomotiv | 12:30 | |
| saturday 25.12.2021 Amur vs Lokomotiv | 10:00 | |
| wednesday 29.12.2021 Lokomotiv vs Spartak | 19:00 | Tickets |
| monday 03.01.2022 Lokomotiv vs Dynamo Msk | 17:00 | Tickets |
| wednesday 05.01.2022 Traktor vs Lokomotiv | 15:00 | |
| friday 07.01.2022 Metallurg Mg vs Lokomotiv | 15:00 | |
| sunday 09.01.2022 Avtomobilist vs Lokomotiv | 15:00 | |
 | thursday 13.01.2022 Lokomotiv vs Ak Bars | 19:00 | Tickets |
| monday 17.01.2022 Kunlun Red Star vs Lokomotiv | 19:30 | |
| wednesday 19.01.2022 Spartak vs Lokomotiv | 19:30 | |
| friday 21.01.2022 Lokomotiv vs SKA | 19:00 | Tickets |
| tuesday 22.02.2022 Ak Bars vs Lokomotiv | 19:00 | |
| thursday 24.02.2022 Dynamo Msk vs Lokomotiv | 19:30 | |
| saturday 26.02.2022 Lokomotiv vs CSKA | 17:00 | Tickets |
| tuesday 01.03.2022 Lokomotiv vs HC Sochi | 19:00 | Tickets |