Schedule
  | friday 10.09.2021 CSKA vs Lokomotiv | 3:1(2:0, 1:1, 0:0) | Review |
 | sunday 12.09.2021 Dinamo R vs Lokomotiv | 0:4(0:4, 0:0, 0:0) | Review |
 | tuesday 14.09.2021 Jokerit vs Lokomotiv | 2:0(1:0, 0:0, 1:0) | Review |
 | monday 27.09.2021 Avangard vs Lokomotiv | 1:4(1:0, 0:1, 0:3) | Review |
 | wednesday 29.09.2021 Vityaz vs Lokomotiv | 1:4(0:0, 0:2, 1:2) | Review |
 | tuesday 05.10.2021 SKA vs Lokomotiv | 1:0(0:0, 1:0, 0:0) | Review |
 | thursday 07.10.2021 Severstal vs Lokomotiv | 1:5(1:2, 0:2, 0:1) | Review |
 | friday 22.10.2021 Barys vs Lokomotiv | 1:4(0:1, 0:1, 1:2) | Review |
 | sunday 24.10.2021 Salavat Yulaev vs Lokomotiv | 4:3 SO(0:1, 0:1, 3:1, 0:0, 1:0) | Review |
 | tuesday 26.10.2021 Dynamo Msk vs Lokomotiv | 4:1(0:0, 3:0, 1:1) | Review |
 | tuesday 02.11.2021 Torpedo vs Lokomotiv | 3:2(1:1, 2:1, 0:0) | Review |
 | monday 15.11.2021 Dinamo Mn vs Lokomotiv | 3:7(2:2, 1:3, 0:2) | Review |
| wednesday 17.11.2021 SKA vs Lokomotiv | 1:3(0:1, 0:1, 1:1) | Review |
 | friday 19.11.2021 HC Sochi vs Lokomotiv | 1:3(0:1, 1:1, 0:1) | Review |
 | sunday 21.11.2021 Neftekhimik vs Lokomotiv | 1:0(1:0, 0:0, 0:0) | Review |
| sunday 28.11.2021 Jokerit vs Lokomotiv | 2:0(0:0, 0:0, 2:0) | Review |
 | tuesday 30.11.2021 Spartak vs Lokomotiv | 1:2 SO(1:1, 0:0, 0:0, 0:0, 0:1) | Review |
| thursday 02.12.2021 CSKA vs Lokomotiv | 1:0 OT(0:0, 0:0, 0:0, 1:0) | Review |
 | tuesday 21.12.2021 Sibir vs Lokomotiv | 2:1 OT(0:0, 0:1, 1:0, 1:0) | Review |
 | thursday 23.12.2021 Admiral vs Lokomotiv | 0:3(0:0, 0:2, 0:1) | Review |
 | saturday 25.12.2021 Amur vs Lokomotiv | 2:4(1:2, 0:1, 1:1 ) | Review |
 | wednesday 05.01.2022 Traktor vs Lokomotiv | 4:3 OT(1:0, 1:1, 1:2, 1:0) | Review |
 | friday 07.01.2022 Metallurg Mg vs Lokomotiv | 3:1(3:1, 0:0, 0:0) | Review |
 | sunday 09.01.2022 Avtomobilist vs Lokomotiv | 15:30 | |
 | monday 17.01.2022 Kunlun Red Star vs Lokomotiv | 19:30 | |
| wednesday 19.01.2022 Spartak vs Lokomotiv | 19:30 | |
 | tuesday 22.02.2022 Ak Bars vs Lokomotiv | 19:00 | |
| thursday 24.02.2022 Dynamo Msk vs Lokomotiv | 19:30 |